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grail cancer screening
This blood test is designed to look for signals of dozens of different cancers in your body—many of which don’t have any routine screening options yet. It analyzes tiny bits of DNA from cancer cells that can show up in your blood long before symptoms appear. It doesn’t replace screenings like colonoscopies or prostate checks, but it’s an extra early-detection layer to catch cancer as early as possible, when it’s most treatable.
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What's included in the test
Adrenal & GI/hepatobiliary
Adrenal cortical carcinoma
Ampulla of Vater
Appendix, carcinoma
Gallbladder
Bile ducts: distal, intrahepatic, perihilar
Stomach
Small intestine
Colon and rectum
Pancreas, exocrine
Gastrointestinal stromal tumor (GIST)
Esophagus & esophagogastric junction
AMMF
Genitourinary & reproductive
Kidney
Bladder, urinary
Prostate
Testis
Penis
Ovary, fallopian tube & primary peritoneum
Uterus: carcinoma & carcinosarcoma; sarcoma
Ureter (and renal pelvis)
Vagina
Vulva
Head & neck
Oral cavity
Larynx
Nasal cavity & paranasal sinuses
Nasopharynx
Oropharynx (HPV-mediated, p16+)
Oropharynx (p16-) & hypopharynx
Skin & soft tissue
Melanoma of the skin
Merkel cell carcinoma
Mesothelioma, malignant pleural
Soft tissue sarcoma*
Bone
Hematologic & lymphoid
Leukemia
Lymphoma (Hodgkin & non-Hodgkin)
Plasma cell myeloma & plasma cell disorders
AMMF
Gynecologic (additional)
Gestational trophoblastic neoplasms
Cervix
Hepatobiliary & thoracic (additional)
Liver
Lung
Neuroendocrine tumors
Neuroendocrine tumors of the appendix
Neuroendocrine tumors of the colon & rectum
Neuroendocrine tumors of the pancreas
FAQs
No. This test is meant to add another layer of early detection, not replace standard screenings like colonoscopies, PSA tests, or skin checks. You still need to stay up to date on those.
It’s recommended for adults who want a more proactive approach to cancer screening—especially those with risk factors like family history, past smoking, or other lifestyle and health risks.
This blood test looks for microscopic DNA “signals” in your blood that may be coming from cancer cells and can screen for signals associated with over 50 different types of cancer from a single draw.
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