Tag: tirzepatide

What is the Difference Between Semaglutide and Tirzepatide?

Posted on by AmyADMIN

When it comes to tackling stubborn weight or managing Type 2 diabetes, Semaglutide and Tirzepatide are the heavy hitters in the game. It’s no secret that these medications are changing lives. But with so much chatter about them, it’s easy to feel overwhelmed. So, what is the difference between Semaglutide and Tirzepatide? Is one better than the other?

On a recent episode of the Women Want Strong Men podcast, we sat down with Anna Griffith, DNP, to get to the bottom of these medications. Now, we’re sharing it all with you so you can make an informed decision about what’s best for your health goals. Check out the episode below, then read on to learn all about the difference between Semaglutide and Tirzepatide.

Semaglutide vs. Tirzepatide: What Are They?

To put it simply, Semaglutide and Tirzepatide are medications used to manage Type 2 diabetes and promote weight loss. They’re both powerful tools that can help people with similar health goals, but they’re not the same. Here’s an easy breakdown: 

  • Semaglutide: A GLP-1 receptor agonist that mimics a natural hormone to regulate blood sugar, slow digestion, and reduce appetite, marketed under brand names like Ozempic and Wegovy.
  • Tirzepatide: A dual GLP-1 and GIP receptor agonist that enhances insulin secretion, reduces hunger, and improves metabolic function, marketed under brand names like Mounjaro and Zepbound.

Like any medication, not everyone has the same success with Semaglutide and Tirzepatide. Some people’s bodies respond better to one over the other, and some may experience side effects on one but not the other. Your health journey is unique, and choosing the right tools to help you achieve your goals is a personal decision. We’re here to help make it easier.

What is the Difference Between Semaglutide and Tirzepatide?

Difference between Semaglutide and Tirzepatide | Man Prepping Semaglutide Injection | Victory Men's Health

As similar as they might seem, there are plenty of differences between Semaglutide and Tirzepatide. Figuring out what those are is the first step in making an informed decision about which medication is right for you. Let’s take a look at how they stack up. 

Mechanism of Action

Semaglutide focuses solely on the GLP-1 receptor, which slows digestion, reduces hunger, and improves blood sugar control. Tirzepatide, on the other hand, activates both GLP-1 and GIP receptors. Experts believe that the added GIP action amplifies weight loss and metabolic benefits.

Efficacy

Both medications are highly effective for weight loss and blood sugar control, but Tirzepatide tends to outperform Semaglutide. In one trial, patients taking Tirzepatide lost an average of 21% of their body weight compared to 15% with Semaglutide.

Side Effects

Nausea is the most common side effect of both medications, often occurring shortly after a first-time dose or dose increase. However, it usually subsides as your body adjusts. Other side effects, like constipation or muscle loss, may also occur but can be managed or prevented with lifestyle changes and personalized dosing like we offer in our clinics. 

Dosing and Administration

Both medications are injectable and follow a weekly dosing schedule with a low starting dose and a monthly titration plan. While both Semaglutide and Tirzepatide are adjusted in a similar way, we tailor the dosing to each patient’s unique needs to ensure the best outcomes. For added flexibility, we also offer compounded options to provide precise dose adjustments.

Semaglutide and Tirzepatide: What’s the Cost?

The cost of these medications varies based on factors like insurance coverage, brand, and whether compounded options are used. Semaglutide’s branded versions typically range from $1,000 to $1,200 per month without insurance. Branded versions of Tirzepatide (Mounjaro and Zepbound) can cost upwards of $1,000 per month.

While compounded versions of Tirzepatide will soon no longer be available per the U.S. Food and Drug Administration (FDA), you can opt for compounded Semaglutide as a cost-effective alternative to branded versions like Ozempic and Wegovy.

For new patients starting Semaglutide at Victory Men’s Health, we charge a flat fee of $355 for the first ten weeks. During this time, we determine the best dosage for you and then adjust the price accordingly based on your specific needs. 

We strive to make our treatments accessible by accepting cost-saving options like HSA (Health Savings Account), FSA (Flexible Spending Account), and Care Credit cards. Our team works closely with patients to ensure affordability without compromising quality.

What are the Health Benefits Beyond Weight Loss?

Medications like Semaglutide and Tirzepatide are major players in improving overall health. Beyond transforming your appearance, they can significantly impact your long-term well-being by addressing underlying health issues. Here are some of the key benefits beyond weight loss:

  • Reduced cardiovascular risk
  • Lower cholesterol levels
  • Improved blood sugar control
  • Decreased visceral fat (aka hormone belly)
  • Reduced stress and anxiety

Does Semaglutide Work Without Lifestyle Changes?

Let’s debunk a common misconception: these medications aren’t magic shots that bring your dreams to life without any effort. They’re tools that can help you succeed, but diet, exercise, and other healthy lifestyle habits are essential for sustainable results.

As we mentioned on the Women Want Strong Men podcast, medications like Semaglutide and Tirzepatide typically make patients more in tune with their body’s signals. Many people find themselves eating smaller portions, avoiding trigger foods, and naturally gravitating toward healthier choices. 

However, you can’t quit these habits after reaching your goals and expect not to regain any weight. You can’t expect long-term results with a short-term solution—it’s up to you to do the work it takes to maintain your new weight.

Questions Our Patients Ask about Semaglutide vs. Tirzepatide

Will I Gain Weight After Stopping Semaglutide or Tirzepatide?

While many studies suggest weight regain can occur after stopping these medications, it’s not inevitable. There are strategies to help you maintain your weight loss, even if you decide to discontinue the medication. 

One key factor is preventing muscle loss, as this helps preserve your basal metabolic rate, making it easier to sustain your results. We support our patients and their goals, whether they choose to stay on a maintenance dose or transition off the medication. With our tools and guidance, it’s entirely possible to maintain your progress long-term.

What if I Don’t Respond to the Medication?

Not everyone responds equally to these treatments. If Semaglutide doesn’t work for you, switching to Tirzepatide might be a viable option. Its dual mechanism can sometimes yield better results for non-responders. It’s best to discuss your options with a healthcare provider who can help you determine the best course of action. 

Is Semaglutide or Tirzepatide Better for Weight Loss?

While both are effective, Tirzepatide generally shows superior weight loss outcomes in clinical trials. However, the best choice depends on your individual needs and health goals.

Do Both Medications Require an Injection?

Yes, both medications are injectable and administered once a week. Compounded versions offer additional flexibility in dosing, allowing us to tailor your treatment to better fit your needs.

When Will I See Results From Semaglutide or Tirzepatide?

Most patients notice changes within the first few weeks, with significant results typically visible within 3-6 months.

Are These Medications Safe for Long-Term Use?

Both Semaglutide and Tirzepatide have been extensively studied for safety and are approved for long-term use. Working with a healthcare provider for regular monitoring and personalized care is the best way to ensure their continued effectiveness and safety.

Transform Your Body and Mind with Victory Men’s Health

Semaglutide and Tirzepatide are transformative medications with incredible benefits for weight loss and overall health. Many of our patients have seen fantastic results with both, so it really comes down to what works best for you. With the right support and care, either one could potentially bring life-changing results. 

At Victory Men’s Health, we specialize in personalized treatment plans designed to match your lifestyle, needs, and goals. Whether you’re looking for help losing weight, boosting testosterone, managing diabetes, or navigating ED, we’re here for you. 


Ready to take the next step? Contact us today to book a consultation and start your journey toward a healthier, happier you.

Tirzepatide for Weight Loss: How Does It Work?

Posted on by AmyADMIN

If you’ve tried everything and still feel like real weight loss is out of reach, you’re not alone. For some, that’s where medications like tirzepatide can make a difference. Marketed under the brand names Mounjaro and Zepbound, tirzepatide for weight loss has become increasingly popular among individuals who haven’t found success with other methods.

At Victory Men’s Health, we offer both semaglutide and tirzepatide as tools for weight loss. While many of our patients have heard of semaglutide, few know what tirzepatide is and how it differs from other weight loss medications. In this blog post, we’re sharing everything you need to know about tirzepatide so you can make more informed decisions about your health. 

Male using tape to measure body size | tirzepatide for weight loss

What is Tirzepatide?

Tirzepatide is a dual-action medication that was originally developed to manage Type 2 diabetes. It was designed to help regulate blood sugar by targeting two hormone receptors at once: GLP-1 and GIP. Sold under the brand name Mounjaro for diabetes or Zepbound for weight loss, tirzepatide’s dual approach has also made it a fantastic tool for weight loss. 

Unlike semaglutide, (marketed under brand names like Ozempic and Wegovy), which only activates GLP-1 receptors, tirzepatide also engages GIP (glucose-dependent insulinotropic polypeptide) receptors. By targeting GIP, the medication’s ability to help with appetite suppression and metabolic regulation is even more powerful. 

Tirzepatide’s dual-action capability means it can be more effective for some patients in achieving and maintaining weight loss—often with fewer side effects.

How Does It Work?

Tirzepatide works by mimicking the natural hormones GLP-1 and GIP, which regulate blood sugar and appetite. Here’s how each hormone plays a role.

  • GLP-1: This hormone curbs hunger by slowing down the rate at which your stomach empties food, making you feel fuller for longer. It also helps reduce blood sugar levels by enhancing insulin sensitivity and reducing sugar production in the liver.
  • GIP: By activating the GIP receptor, tirzepatide amplifies the effects of insulin, especially after meals, and further contributes to the feeling of fullness. The combination of these two hormones helps lower calorie intake and minimizes the likelihood of fat storage.

Tirzepatide vs. Semaglutide: What’s the Difference?

At Victory Men’s Health, we offer both tirzepatide (Mounjaro) and semaglutide (Ozempic or Wegovy) to help our patients reach their weight loss goals. Both can be effective, but there are some key differences to consider before deciding which one is right for you. 

  • Dual-Action Mechanism: Tirzepatide activates both GLP-1 and GIP receptors, while semaglutide targets only GLP-1. This dual action in tirzepatide can lead to greater appetite suppression.
  • Weight Loss Effectiveness: Studies show tirzepatide users see an average weight reduction of about 20% of body weight, compared to around 15% with semaglutide.
  • Ideal Fit: Semaglutide works well for those who respond effectively to GLP-1 alone, while tirzepatide may be better for individuals who need additional support to control their appetite and blood sugar.

Our team will help you determine which option aligns best with your needs and health goals for a personalized, effective weight loss treatment plan. On an episode of the Women Want Strong Men podcast, nurse practitioner Anna Griffith shared her expert insights on semaglutide and tirzepatide. Check it out below and keep reading to learn more about tirzepatide.

Benefits of Tirzepatide for Weight Loss

Weight loss isn’t just about hitting a lower number on the scale—it’s about improving your overall health so you can feel stronger and live better. For many men, extra weight comes with increased risks of cardiovascular disease and other health issues. Tirzepatide addresses these risk factors for benefits that go beyond your physical appearance.

At Victory Men’s Health, we’re particularly fond of tirzepatide for its ability to reduce visceral fat—the belly fat that wraps around your organs and contributes to serious health issues. By targeting both GLP-1 and GIP hormones, this weight loss medication helps bring balance to your body in a way that benefits your energy levels, heart health, and metabolic function.

Here’s a closer look at the key benefits of tirzepatide: 

  • Improved Cardiovascular Health – Studies have shown that GLP-1 medications can reduce the risk of cardiovascular issues. For men, weight loss plus cardiovascular support means a lower risk of high blood pressure, heart disease, and other age-related conditions.
  • Better Cholesterol and Blood Sugar Levels – Tirzepatide helps stabilize blood sugar and can positively impact cholesterol levels, which is essential for reducing the risk of diabetes, metabolic syndrome, and other health complications.
  • Reduced Visceral Fat – This medication particularly helps in reducing visceral fat—the type that surrounds organs like the liver. Visceral fat is associated with higher risks of heart disease and other metabolic disorders, making its reduction a big win for long-term health.

What are the Side Effects of Tirzepatide?

Like any medication, tirzepatide comes with potential side effects, although they’re generally mild and manageable. Here’s what to watch for and some practical tips to minimize discomfort.

  • Nausea: Nausea is common among tirzepatide users, especially at the start or after increasing the dose. To manage this side effect, try eating smaller meals throughout the day, avoid heavy or fried foods, drink plenty of water, and consider natural remedies like ginger lozenges or tea.
  • Constipation: Some people experience constipation with tirzepatide. Staying hydrated (aim for half your body weight in ounces daily) and increasing your fiber intake from whole foods like vegetables and fruits can help. Adding gentle physical activity, like walking, can also improve digestion.
  • Muscle Loss: When losing weight, it’s not uncommon to lose muscle alongside fat. To combat this, we recommend a balanced diet with adequate protein (0.7–1 gram of protein per ideal pound of body weight) and strength training exercises. Monitoring not only weight, but muscle mass and body fat percentage, is key to ensuring muscle loss is minimal to none. 

Most of our patients find that these side effects subside as their body adjusts to the weight loss medication. If issues persist, your healthcare provider may recommend adjusting the dosage or using other personalized strategies to alleviate symptoms.

Who Should Consider Tirzepatide for Weight Loss?

Tirzepatide may be right for you if you’re looking for an effective weight-loss solution that offers metabolic and cardiovascular benefits. Ideal candidates include individuals who:

  • Have a BMI or body fat percentage in the overweight or obese range and are struggling to lose weight through diet and exercise alone.
  • Are managing or at risk for metabolic health issues such as prediabetes or Type 2 diabetes.
  • Have tried other weight loss medications or programs without the desired results.

At Victory Men’s Health, we take a personalized approach to weight loss, evaluating each patient’s health profile, goals, and lifestyle before recommending tirzepatide or any medication.

Questions Our Patients Ask About Tirzepatide

How Quickly Do You Lose Weight on Tirzepatide?

Weight loss can vary, but many patients start seeing noticeable results within the first few weeks. Progress generally continues as your body adjusts to the medication and any necessary lifestyle changes.

How Can I Lose More Weight on Tirzepatide?

Combining tirzepatide with a high-protein, low-processed food diet and incorporating strength training can help you maximize weight loss without losing muscle. 

What Should You Avoid While Taking Tirzepatide?

Avoid foods that may cause nausea, like fried or overly sugary items. Excessive alcohol consumption may also trigger side effects, so it’s best to limit intake while on this medication.

Will I Gain Weight After Stopping Tirzepatide?

Some weight regain can happen if you don’t maintain lifestyle changes. However, continuing healthy habits like mindful eating, regular exercise, and a balanced diet can help you sustain your progress long after you’ve stopped tirzepatide. 

How is Tirzepatide Different from Semaglutide?

Tirzepatide acts on both GLP-1 and GIP receptors, while semaglutide only targets GLP-1. This dual action often makes tirzepatide more effective for weight loss. 

Can You Take Other Medications with Tirzepatide?

It depends on the medication. Our providers carefully review each patient’s medication list to prevent any adverse interactions and ensure a safe treatment plan.

Start Your Weight Loss Journey with Victory Men’s Health

Tirzepatide offers an effective, science-backed way to tackle weight loss and improve overall health. Unlike other weight loss solutions, this medication’s dual-hormone approach makes it uniquely effective at curbing appetite, stabilizing blood sugar, and reducing visceral fat. 

If you’re interested in exploring tirzepatide as part of your weight loss journey, we’re here to help. Our team of experts are committed to personalized care, offering in-person and telehealth consultations to make your journey as convenient as possible. 


Contact us today to book a consultation and determine if tirzepatide is right for you.